Delhi · Gurugram · Bangalore · Baddi · Bahadurgarh

Vitamin & Mineral Assay | HPLC, ICP-OES, ICP-MS | NABL Accredited

Under-strength vitamin and mineral assays are the single largest cause of FSSAI Section 53 misleading-advertisement enforcement and marketplace delisting on supplement SKUs. Backed by the Arbro Group's unbroken NABL accreditation since 2003, Auriga Research delivers analytical vitamin and mineral assay across the full pharmacopoeial scope for health supplements, dietary supplements, and functional foods.

Vitamin and mineral content in supplements is regulated under the FSS (Health Supplements, Nutraceuticals, Food for Special Dietary Use, FSMP, Functional Food and Novel Food) Regulations 2016 with reference to ICMR-NIN RDA values and FSSAI Schedule VII Upper Tolerable Intake Levels. Our scope covers HPLC-UV / DAD / FLD for water- and fat-soluble vitamins, microbiological assay for B12 and folate at trace levels, ICP-OES for major minerals (Ca, P, K, Na, Mg), and ICP-MS for ultra-trace elements (Se, Cr, I, Mo) and complex matrices.

Every assay report includes the analytical value, label declared value, percentage of label claim, and method reference — the exact data points FSSAI assessors, marketplace listing teams, and procurement auditors look for.

Reports in 10–14 working days | Express: 7 days available
Get a Quote Call +91-7428116100

Assay Methods & Parameters

Each parameter is mapped to its AOAC or pharmacopoeial method so QA and regulatory teams can match scope to FSSAI / IP / USP requirements at a glance.

HPLC-UV

Vitamin C (Ascorbic Acid)

HPLC-UV at 245 nm per AOAC 967.21 — stabilised extraction with metaphosphoric acid to prevent oxidation during analysis.

HPLC-UV

Vitamin B1 (Thiamine)

HPLC-UV per AOAC 942.23 / IP 2018 — thiochrome derivatisation for fluorescence detection at trace levels.

HPLC-DAD

Vitamin B2 (Riboflavin)

HPLC-DAD at 270 / 444 nm per AOAC 970.65 — native fluorescence available for trace-level applications.

HPLC-UV

Vitamin B3 / B5 / B6

HPLC-UV per AOAC 944.13 (niacin) / AOAC 945.74 (pantothenic acid) / AOAC 985.32 (pyridoxine) — single-run separation available.

Microbiological

Vitamin B12 (Cyanocobalamin)

Microbiological assay using Lactobacillus delbrueckii per AOAC 952.20 / IP 2018 — required where label claims are below HPLC sensitivity (µg-level).

Microbiological

Folate (B9 / Folic Acid)

Microbiological assay using Lactobacillus rhamnosus per AOAC 992.05 — separates free folate from polyglutamyl folate using tri-enzyme treatment.

HPLC-UV

Vitamin A (Retinol + Beta-Carotene)

HPLC-UV per AOAC 992.04 / 992.06 with saponification — separates retinol, retinyl esters, and total beta-carotene quantification.

HPLC-UV

Vitamin D2 / D3

HPLC-UV at 265 nm per AOAC 995.05 — separates ergocalciferol (D2) from cholecalciferol (D3) with saponification step.

HPLC-FLD

Vitamin E (Tocopherols)

HPLC-FLD per AOAC 988.18 — separates alpha, beta, gamma, delta tocopherol and tocotrienol isomers.

HPLC-UV

Vitamin K1 / K2

HPLC-UV per AOAC 999.15 with reductive electrochemical detection where required — separates phylloquinone (K1) from menaquinone (K2 forms MK-4, MK-7).

ICP-OES

Major Minerals (Ca, P, K, Na, Mg)

ICP-OES per AOAC 984.27 with microwave digestion — single-run multi-element quantification of major macro-minerals at mg-level sensitivity.

ICP-MS

Trace Minerals (Fe, Zn, Cu, Mn, Cr, Se, Mo, I)

ICP-MS per AOAC 2015.01 — single-run multi-element quantification at trace µg-level required for chromium picolinate, selenomethionine, and iodine supplements.

How It Works

1

Get a Quote

Share your product type and the parameters you need tested. Your dedicated SPOC will confirm the testing scope, the applicable method, and the exact sample quantity required for your specific panel before you dispatch anything.

2

Send Your Sample

Dispatch your sample with a completed Test Request Form to the nearest Auriga lab. Each sample is individually bar coded and registered in YLIMS, Auriga's in-house Laboratory Information Management System, upon receipt. Testing begins within 24 hours of sample registration.

3

Testing and QA Review

Your sample is tested against the confirmed validated method by Auriga's scientific team. Every result passes through a formal internal QA review and sign-off before the report is generated.

4

Receive Your NABL Report

Your NABL-accredited test report is delivered digitally within the committed turnaround time. Reports carry Auriga's NABL accreditation under ISO/IEC 17025:2017 and are accepted by FSSAI under the Health Supplements Regulations 2016, BIS, and international buyers. You can track your sample status in real time through YLIMS at any point in the process.

Turnaround Time

Panel Standard TAT Express
Single vitamin or mineral assay 5–7 working days 3 days
Standard multi-vitamin panel (5–10 vitamins) 7–10 working days 5 days
Major + trace mineral panel by ICP-OES / ICP-MS 7–10 working days 5 days
Full vitamin + mineral panel (10–18 nutrients) 10–14 working days 7 days
Vitamin B12 / Folate microbiological assay 10–12 working days
Specialised nutrient (CoQ10, lutein, carnitine, taurine) 7–10 working days Available

Who Needs This Testing

  • Nutraceutical manufacturers preparing FSSAI Form B nutraceutical licence applications and renewals under the Health Supplements Regulations 2016.
  • D2C supplement brands launching multi-vitamin / multi-mineral SKUs on Amazon, Flipkart, Blinkit, Zepto, and BigBasket.
  • Sports nutrition and wellness brands needing assay-verified data for label claim defence against marketplace and FSSAI surveillance.
  • Brands using fortified premixes — assay-verifying the premix supplier's certificate of analysis on each batch released to production.
  • Functional food and beverage brands (energy drinks, malt-based health drinks, fortified yogurt) substantiating vitamin and mineral claims.
  • Mineral supplement brands (calcium, iron, zinc, magnesium) needing ICP-OES verification of declared elemental content vs label.
  • Brands building stability dossiers — assay at each ICH stability time point to confirm 80%-of-claim floor through shelf life.

Why Auriga for Vitamin & Mineral Assay

Unbroken NABL accreditation since 2003

Arbro Group has held NABL ISO/IEC 17025 accreditation continuously since 2003 covering AOAC, IP, and USP vitamin and mineral assay methods.

Full HPLC + microbiological + ICP toolkit

HPLC for vitamins, microbiological assay for B12 and folate at trace level, ICP-OES for major minerals, and ICP-MS for ultra-trace elements — no method gap, no partner-lab dependency.

Multiple ICP units across the network

Five ICP-MS / ICP-OES instruments across Delhi, Manesar, Bangalore, and Baddi — capacity for full multi-element panels with express turnaround.

Label-ready output

Reports include analytical value, label value, %-of-claim, and method reference — formatted for direct paste into label dossiers and FSSAI submissions.

Dual NABL + FSSAI notification

Reports carry evidentiary weight under FSS Act 2006 for nutraceutical licence applications, surveillance responses, and marketplace listing reviews.

Five regional labs

Delhi, Gurugram, Bangalore, Baddi, and Bahadurgarh — closer to your factory or warehouse means lower sample-courier risk and faster despatch.

Frequently Asked Questions

Which vitamins and minerals are tested for nutraceuticals?
Auriga provides assay services for all FSSAI- and pharmacopoeially-relevant vitamins and minerals: water-soluble vitamins (C, B1, B2, B3, B5, B6, B7, B9 folate, B12); fat-soluble vitamins (A retinol, D2/D3, E tocopherols, K1/K2); major minerals (Ca, P, K, Na, Mg); trace minerals (Fe, Zn, Cu, Mn, Cr, Se, Mo, I); and specialised nutrients (choline, inositol, taurine, CoQ10, lutein, lycopene, carnitine).
What methods are used for vitamin and mineral analysis?
HPLC with UV / DAD / FLD detection per AOAC and pharmacopoeial methods for water-soluble and fat-soluble vitamins; microbiological assay per AOAC 952.20 / IP 2018 for B12 and folate where HPLC sensitivity is insufficient; ICP-OES for major and trace minerals at mg-to-µg per kg sensitivity; ICP-MS for ultra-trace elements (Se, Mo, Cr) and where samples have complex matrices; iodometry / colorimetry for iodine where ICP-MS is not appropriate.
What are FSSAI RDA reference levels for supplements?
FSSAI references the Recommended Dietary Allowance (RDA) from the ICMR-NIN Indian Dietary Allowances. Health supplement single-serving doses are constrained at 1× to 1.5× RDA for most vitamins and minerals under the Health Supplements Regulations 2016, with higher doses permitted only as part of nutraceutical and FSMP categories. Upper Tolerable Intake Levels (ULs) from FSSAI Schedule VII apply where overdose risk is established (Fe, Vit A, Vit D, Se).
How long does vitamin and mineral assay take?
Single-vitamin assay (e.g., vitamin C, B12, D3) takes 5–7 working days. Standard multi-vitamin / multi-mineral panel of 10–18 nutrients takes 10–14 working days. Methods involving microbiological assay (B12, folate) take a fixed 10–12 day incubation cycle regardless of express priority. Express service at 7 working days is available for HPLC-only assay panels.
What sample quantity is required?
Send at least 60 g of finished product or 60 dose units (tablets, capsules, sachets) in sealed retail packaging. For multivitamin / multimineral combination panels, the quantity scales with the number of distinct nutrients tested. Different flavour variants, pack sizes, or production batches require separate samples. Our SPOC will confirm the exact requirement after reviewing the formulation and label.
What does the assay report include?
Each NABL-accredited assay report includes: (a) nutrient name and CAS / pharmacopoeial reference; (b) analytical value per unit and per serving; (c) label declared value for comparison; (d) % of label claim — the FSSAI substantiation figure; (e) method reference (AOAC / IP / USP / pharmacopoeial); (f) limit of detection / quantification for trace-level nutrients; (g) uncertainty of measurement per ISO/IEC 17025 requirement.
When is re-assay required?
Re-assay is required whenever: (a) the active premix supplier or grade changes; (b) the formulation overage strategy changes; (c) the manufacturing site or process changes; (d) the packaging system (especially moisture-barrier blister or sachet) changes; (e) stability data shows degradation approaching the 80% FSSAI floor. Annual re-assay supports surveillance defence on stable formulations.

Get Your Vitamin & Mineral Assay Quote

HPLC, microbiological assay, ICP-OES, and ICP-MS — full vitamin and mineral panels under one NABL-accredited roof. Label-ready output for FSSAI Form B dossiers.

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